They were once again interrupted, as the Empire announced that it was imposing a curfew on the Tatoo system, effective immediately. Later that year, the Modal Nodes played a performance of "Mad About Me" for an interplanetary Imperial broadcast about life on Tatooine. Where a band more experienced with the cantina would have continued to play in harmony with the chaos around them, the Modal Nodes promptly stopped, but when the fracas had died down they picked up where they had left off and finished the song. As the situation turned violent, Kenobi brought out his lightsaber and cut off Baba's arm. Shortly after their performance began, Kenobi and Skywalker arrived upon entering, Skywalker was harassed by two of the patrons, Ponda Baba and Cornelius Evazan. On the day the Jedi Obi-Wan Kenobi and his protege Luke Skywalker came to Mos Eisley in search of transport off Tatooine, the band squabbled over their choice of song before choosing "Mad About Me." The band, however, was unaccustomed to performing at places like Chalmun's, and their performance of it was off both key and tempo, glaringly noticeable to patrons with sensitive hearing like the Chadra-Fan Kabe. In 0 BBY, the Modal Nodes got a job as the regular band at Chalmun's Spaceport Cantina in Mos Eisley. The tune, though fairly nondescript, was bouncy, and the Modal Nodes' rendition of it was particularly upbeat. By 0 BBY, the song had become a favorite of the Bith jizz band Figrin D'an and the Modal Nodes. The Toydarian junk dealer Watto often hummed the tune to himself in his shop in Mos Espa, on the planet Tatooine. "Mad About Me" was written at some point before 3643 BBY.
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She noted 2 relevant trials that studied concurrent versus sequential immunotherapy-KEYNOTE-189 (NCT02578680), which examined platinum chemotherapy plus pemetrexed with or without pembrolizumab (Keytruda), and KEYNOTE-407 (NCT02775435), which looked at carboplatin plus paclitaxel or nab-paclitaxel (Abraxane) chemotherapy with or without pembrolizumab. 1 “For a majority of our patients who do not have oncogenic-driven cancers, there is now overwhelming and compelling data for the role of immune checkpoint inhibitors, either with chemotherapy or as monotherapy in the first-line setting,” acknowledged Kelly. While the use of immune checkpoint inhibitors, as a monotherapy and in combination with chemotherapy, has demonstrated benefits for patients with NSCLC, the key to unlocking the full therapeutic potential for these treatments, said Kelly, an associate director for clinical research at the University of California Davis Comprehensive Cancer Center, lies in the timing of treatment initiation. At the 17th Annual Winter Lung Cancer Conference ®, hosted by Physicians’ Education Resource ®, LLC, presentations from Karen Kelly, MD and Gilberto de Lima Lopes, MD, looked for answers to address these issues. Although accumulating data continue to show immunotherapy as a major step forward in the treatment of patients with non–small cell lung cancer (NSCLC), questions regarding optimal sequencing and treatment duration still remain. Please read our Terms of Service and Privacy Policy before using any of the features or services that we provide. 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